Acromegaly - Octreotide (C2L)

Acromegaly is a rare and serious condition related to the
hypersecretion of growth hormone by the pituitary gland,
generally of tumoral origin. This causes an uncontrolled growth of organs, debilitating symptoms and a shorter life expectancy.

Pharmacotherapy with somatostatin analogs is one of the treatment options, a life-long treatment with a few and mild side effects. Novartis’ Sandostatin® (octreotide) is the market leader and which efficacy is clearly established for treating acromegaly. The yearly treatment with the long-acting release (LAR) formulation of the product, which consists of intramuscular injections every 4 weeks, is costly. Difficult reconstitution prior to injection is also an issue.

The safety and efficacy of the product are currently under study.

Licensing & Divestment

Ambrilia’s C2L is available for licensing or divestment. For more information, please contact:

Richard La Rue, LL.L, D.D.N.
Interim President & CEO
Tel.: (514) 751-3002 ex. 269
e-mail: rlarue@ambrilia.com

Sandostatin®LAR is a registered trademark of Novartis Pharmaceuticals

 

 

Octreotide (C2L)

Improved formulation of Sandostatin®LAR

Indication

Acromegaly and rare gastrointestinal tumors

Development status

Phase III

Patents

Patented delivery system technology

Partners

Archimedes Pharma: U.K.

Gerolymatos: Greece, Turkey and other countries

Kwidza Pharma: Austria

Omega: Canada, Egypt

Pharmis: Portugal, Brazil

Shin Poong: Korea

Genepharm Limited: Australia & New Zealand